What is Crohn's disease?
Crohn's disease is a inflammatory bowel disease (IBD), and characterized by a large number of scattered granulomas, which are grains or granules in response to chronic infection, inflammation.
The Crohn's disease mainly affects people at the age from 15~30 years old, but any age groups may suffers from this disease. Once you are diagnosed with this disease, even if they are treated, there is also a tendency to relapse.
What causes Crohn's disease?
- Bacteria are considered as a main cause of Crohn's disease, particularly the Mycobacterium paratuberculosis;
- Some pathogenic microorganisms, foods, antigens may encourage the outburst of Crohn's disease;
- Genetic factors;
- Immune response.
Crohn's disease symptoms
- Lower right abdominal pain or pain around the navel;
- Abdominal pain intensified after eating, and mitigated after excretion;
- Severe, continued pain, if complicated with intestinal obstruction, peritonitis, intestinal perforation.
- Mushy stool, generally no mucus and no blood in stool;
- If Crohn's disease involves low segment of colon, rectum and anus, you may have blood and mucus in stool.
- Inflammatory mass;
- In the lower right abdomen and/or around the navel;
- Seen in 10%~20% patients.
- Characteristic change;
- Fistula is formed through the perforated bowel to other bowel segments, bladder, vagina, abdominal wall or skin around anus.
- Anal fissure, abscess surrounding the rectum and anal canal, and anal fistula;
- Having a fever;
Blood in stool
If the Crohn's disease is complicated with intestinal perforation, it will lead to intestinal bleeding and subsequent blood in stool.
If the Crohn's disease involves low segment of colon, rectum and anus, it will promote the formation of anal fissure, anal fistula, which are common causes of rectal bleeding, anal bleeding and blood in stool.
Last update: 2012-08-01